MainosMemos: 3/17/13

Saturday, March 23, 2013

Pioneers of cortical plasticity: six classic papers by Wiesel and Hubel

Wiesel TN, Hubel DH. Effects of visual deprivation on morphology and physiology of cells in the cat's lateral geniculate body. J Neurophysiol 26: 978-993, 1963 (http://jn.physiology.org/cgi/reprint/26/6/978).

Hubel DH, Wiesel TN. Receptive fields of cells in striate cortex of very young, visually inexperienced kittens. J Neurophysiol 26: 994-1002, 1963 (http://jn.physiology.org/cgi/reprint/26/6/994).

Wiesel TN, Hubel DH. Single-cell responses in striate cortex of kittens deprived of vision in one eye. J Neurophysiol 26: 1003-1017, 1963 (http://jn.physiology.org/cgi/reprint/26/6/1003).

Wiesel TN, Hubel DH. Comparison of the effects of unilateral and bilateral eye closure on cortical unit responses in kittens. J Neurophysiol 28: 1029-1040, 1965 (http://jn.physiology.org/cgi/reprint/28/6/1029).

Hubel DH, Wiesel TN. Binocular interaction in striate cortex of kittens reared with artificial squint. J Neurophysiol 28: 1041-1059, 1965 (http://jn.physiology.org/cgi/reprint/28/6/1041).

Wiesel TN, Hubel DH. Extent of recovery from the effects of visual deprivation in kittens. J Neurophysiol 28: 1060-1072, 1965 (http://jn.physiology.org/cgi/reprint/28/6/1060).

Comments: Read this paper...then the original articles. DM

The improving outcomes in intermittent exotropia study: outcomes at 2 years after diagnosis in an observational cohort

The improving outcomes in intermittent exotropia study: outcomes at 2 years after diagnosis in an observational cohort

....At follow-up, data were available for 371 children (81% of the original cohort). .... 0.5% (2/371) children developed constant exotropia. The surgically treated group was the only group with clinically significant improvements in angle or Newcastle Control Score. ... 8%... of those treated surgically required second procedures for overcorrection within 6 months of the initial procedure and at 6-month follow-up 21% (13) were overcorrected....

Comments: The folks in the UK have been doing some outstanding research in the area of strabismus surgery outcomes. I certainly congratulate them!! Unfortunately, most strabismus surgery outcomes really show that for many patients strabismus surgery may not be ready for prime time just yet and an alternate form of treatment should be considered. Optometric vision therapy should be one of the first treatment options considered prior to any surgical intervention. Go to http://covd.org, http://oepf.org and/or http://aoa.org to find a doc who can help. If you click on the title above you can read the full article. DM

Friday, March 22, 2013

Announcement of Webinar to Discuss Results of NEI Funded Research Study

	Pediatric Eye Disease Investigator Group
	Coordinating Center
	15310 Amberly Drive, Suite 350
	Tampa, FL 33647
	Tel: (888) 797-3344
	Fax: (888) 697-3344
	Email: [email protected]

To: Pediatric Eye Care Provider

Subject: Announcement of Webinar to Discuss Results of NEI Funded Research Study

On April 8^th, at 9pm EST (8pm CST, 7pm MST, 6pm PST), we will be hosting a webinar to present the results of the recently completed randomized clinical trial, Amblyopia Treatment Study-15, which was conducted by the Pediatric Eye Disease Investigator Group (PEDIG) and funded by the National Eye Institute of the National Institutes of Health. We are inviting you to attend the webinar.

The purpose of the ATS-15 study was to determine if increasing prescribed patching dosage improves amblyopic eye visual acuity in those 3 to <8 .="" year-olds--="">

As a member of the eye care community, you are invited to join your colleagues for this live 30-minute web presentation. Dr. David Wallace (Duke University, Department of Ophthalmology), the ATS-15 Study Chair will be presenting the results of the study prior to publication.

This webinar will consist of a 20-minute presentation followed by a 10-minute Q & A session.

We hope that you will be able to join us for this webinar.

When: Monday April 8, 2013 at 9pm EST (8pm CST, 7pm MST, 6pm PST)

Webinar Instructions: You will need to use the URL below to register.

https://attendee.gotowebinar.com/register/7034652653742061312

Information will be sent to the email used in your registration with your personal link.

A reminder email will be sent 1 day and 1 hour before the start of the webinar from [email protected] with your personal link included.

You will be prompted to download and install software when attempting to enter the webinar. 30 minutes prior to the start, the session will be open allowing those who need to download and install the software to do so (Please note that GoTo Meeting and GoTo Webinar are different programs). If you need to inform your IT department of this installation, please do so prior to the webinar.

Questions can be asked by typing in the chat box and will be answered during the Q&A session.

Please write questions out completely even if it is a follow up to another question.

Microphones of the attendees will be muted during the webinar.

If you have any questions feel free to contact Curtis Koh at 1-888-797-3344 or [email protected]

Announcement of Webinar to Discuss Results of NEI Funded Research Study

	Pediatric Eye Disease Investigator Group
	Coordinating Center
	15310 Amberly Drive, Suite 350
	Tampa, FL 33647
	Tel: (888) 797-3344
	Fax: (888) 697-3344
	Email: [email protected]

Announcement of Webinar to Discuss Results of NEI Funded Research Study

The purpose of the ATS-15 study was to determine if increasing prescribed patching dosage improves amblyopic eye visual acuity in 3 to <8-year-old 2="" amblyopia="" and="" apparently="" children="" correction="" daily="" following="" hours="" initial="" of="" optimum="" patching.="" prescribed="" refractive="" residual="" span="" stable="" treatment="" with="">

As a member of the eye care community, you are invited to join your colleagues for this live 30-minute web presentation. Dr. David Wallace (Duke University, Department of Ophthalmology), the ATS-15 Study Chair will be presenting the results of the study prior to publication.

This webinar will consist of a 20-minute presentation followed by a 10-minute Q&A session.

We hope that you will be able to join us for this webinar.

When: Monday April 8, 2013 at 9pm EST (8pm CST, 7pm MST, 6pm PST)

Webinar Instructions: You will need to use the URL below to register.

https://attendee.gotowebinar.com/register/7034652653742061312

Information will be sent to the email used in your registration with your personal link.

A reminder email will be sent 1 day and 1 hour before the start of the webinar from [email protected] with your personal link included.

Questions can be asked by typing in the chat box and will be answered during the Q&A session.

Please write questions out completely even if it is a follow up to another question.

Microphones of the attendees will be muted during the webinar.

If you have any questions feel free to contact Curtis Koh at 1-888-797-3344 or [email protected]

Thursday, March 21, 2013

Long-term follow-up of bilateral botulinum toxin injections versus bilateral recessions of the medial rectus muscles for treatment of infantile esotropia

Long-term follow-up of bilateral botulinum toxin injections versus bilateral recessions of the medial rectus muscles for treatment of infantile esotropia

...The mean number of injections in successfully treated botulinum group patients was 1.4. The success rate was similar in the botulinum (68%) and surgery (77%) groups.....

Comments: When botulinum toxin is used versus surgical intervention for strabismus, the failure rate is still about 30%. DM

Wednesday, March 20, 2013

Surgical intervention in childhood intermittent exotropia: current practice and clinical outcomes from an observational cohort study

Surgical intervention in childhood intermittent exotropia: current practice and clinical outcomes from an observational cohort study

.....35% of patients had excellent, 28% had fair and 37% had poor primary outcome. .... Satisfactory control was achieved in 65% of patients, while X(T) remained/recurred in 20%. Persistent over-correction occurred in 15% of children..... 40% of those initially over-corrected remained so by last postoperative assessment.....

Comments: 65% of the patients only achieved a fair or worse a poor outcome. 40% were over corrected ad remained that way. Before surgery is attempted, a consultation with a developmental optometrist is suggested. Go to http://covd.org to find such a doctor. DM

Severe complications of strabismus surgery

Severe complications of strabismus surgery

.... The most common reported complication was perforation of the globe..., followed by ... slipped muscle..., severe infection..., scleritis ..., and lost muscle..... Complications with the potential for a poor outcome are relatively common.....

Comments: Please note that most strabismus surgery most of the time does not result in one or more complications, however, these complications are often not discussed or glanced over by all involved. It is important for the medical consumer to do their due diligence and to be aware of unwanted side effects of medical intervention. DM

Tuesday, March 19, 2013

Exotropia in children with high hyperopia

.....Children with high hyperopia and exotropia are likely to have developmental delay or other systemic diseases, amblyopia, and poor stereopsis. Treatment of high hyperopia in exotropic children with their full cycloplegic refraction can result in excellent alignment.....

Comments: The power of a pair of glasses! Many doctors (and patients) do not realize the therapeutic power of a pair of glasses. All too often we discount the "medcine in the glasses" and only consider the fashion sense (blue ones to go with blue outfits, green ones to go with green outfits) and cosmetic appeal. Use your refractive prescriptive powers to help your patients overcome vision problems above and beyond your typical approach to refractive care. DM

Save Your Vision Month: Schedule Your Eye Examination Today

This is Save Your Vision Month and you should Schedule Your Eye Examination Today with your family optometrist. To find an optometrist in your neighborhood go to the American Optometric Association, College of Optometrists in Vision Development, Optometric Education Foundation Foundation and the American Academy of Optometry websites.

Don't have a family optometrist in Chicago? Check out Lyons Family Eye Care right now!