Saturday, February 1, 2014

Exploring inhibitory deficits in female premutation carriers of fragile X syndrome: Through eye movements.

Shelton AL1Cornish K1Kraan C1et al .Exploring inhibitory deficits in female premutation carriers of fragile X syndrome: Through eye movements. 2014 Jan 11;85C:201-208. doi: 10.1016/j.bandc.2013.12.006. [Epub ahead of print]

.......Group comparisons revealed poorer inhibitory control for female premutation carriers on ocular motor tasks, in addition to demonstrating some difficulties in behaviour self-regulation, when compared to controls. A negative correlation between CGG repeat length and antisaccade error rates for premutation carriers was also found. Our preliminary findings indicate that impaired inhibitory control may represent a phenotype characteristic which may be a sensitive risk biomarker within this female fragile X premutation population......

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